HIV and AIDS Acquired Immune Deficiency Syndrome
The epidemiological relationship between HIV Human Immunodeficiency virus & AIDS is casual and appears not to be related.
HIV virus has never been isolated. Direct isolation & purification of the so called HIV virus from the blood of an AIDS patient or from an HIV +ve individual has never been reported.
Electron microscopic evidence that has been reported has originated from cell culture systems & never directly from patients. Till date publications of Electron microscopy pictures of HIV have not satisfied the morphological features required for diagnosis of retroviral particles.
For confirming the presence of HIV virus, there is a mandatory requisite of reverse transcriptase activity. In case of HIV, this activity is not of viral origin but of cellular debris origin, the result of processing the tissue sample examined.
The PCR test
The PCR test used to measure viral load in patients is not a scientifically approved method. Even when PCR shows high viral load Electron microscopy has never correlated by demonstration of the HIV particle from the plasma.
There are certain scientific criteria required to prove that any infective disease is caused by a germ. HIV virus does not satisfy Koch’s postulates or the Bradford–Hill criteria required for proving itself as an infection or as the cause of AIDS.
Dubious definition of AIDS?
Acquired Immuno Deficiency Syndrome is defined as the presence of one or more of 30 (AIDS defining) illnesses. This definition holds true even if the evidence of HIV infection is absent.
While TB with HIV is AIDS, many diseases are classified as AIDS without the HIV +ve status. for e.g. Kaposi’s sarcoma is AIDS, even if HIV negative.
Furthermore, Many of the AIDS defining diseases may be present without immunodeficiency, eg Kaposis sarcoma may occur without underlying immunodeficiency. Hence whether AIDS is contagious or sexually transmitted can be logically questioned.
HIV +VE may not mean that the patient has HIV infection
HIV testing is done by ELISA & WESTERN BLOT tests, both of which are non-specific.
70 different diseases or conditions can cause false positive HIV test. E.g. hepatitis, leprosy, TB, renal failure, influenza, tetanus or other vaccination, respiratory infection, pregnancy, malaria, circulating immune complexes, Rheumatoid arthritis, SLE, CT disease, Cancers, lymphoma, multiple blood transfusions, jaundice, Multiple sclerosis, Anti sperm antibodies – as in anal intercourse, Epstein Barr virus, HLA antibodies, blood antibodies, etc.
So one may end up with a verdict of HIV +ve for a lifetime, by mere virtue of having suffered another unrelated disease (without any connection to HIV)
Immunodeficiency and Opportunistic Infections
Immunodeficiency refers to a deviation of some parameters of immunity and not complete immune absence. Immunity is of two types; Acquired and Innate (by birth) Immunodeficiency is not necessarily a decrease in overall immunity, but a decrease in acquired immunity, while preserving the innate immunity of birth.
Thus failure of nonspecific immune mechanisms causes AIDS.
Interestingly, Stress syndrome caused by any severe unrelated illness can cause a fall in T cell count. This is because catabolic states of illness causes muscle breakdown and a fall in proteins required for cellular defence mechanisms. This leads to T cell deficiency, which will suppress the body’s symbiotic bacteria causing vacant spaces in tissues. Opportunistic germs are quick to occupy this vacancy and multiply to cause Opportunistic infections.
HIV treatment with drugs
Many drugs used to treat AIDS are immune-suppressants themselves, so their use cannot be justified to treat Immunodeficiency.
These drugs are immuno-toxic & may cause a fall in immunity and sometimes precipitate any of the 30 AIDS defining illnesses. Besides lifelong therapy with these immuno-suppressants will not only kill viral DNA (beneficial) but also human cellular DNA as an adverse effect.
The consequence of severe drug toxicity may be death, so death by AIDS may also be because of drug overtreatment and not just because of the AIDS disease process.
Independent researchers of Clinical Immunology in New York have said that AIDS may be a toxic nutritional syndrome caused by immunological stressor agents.
INTERNATIONAL CONFERENCE ON VALIDITY OF HIV / AIDS PROGRAMME, Academy of Nutrition improvement, Nagpur, 30 Jan 2000
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